Careers at Editas
Research Associate, Cellular Process Development – 1045 – Cambridge, MA
Location – Cambridge, MA
What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize trans-formative, durable, precision genomic medicines for many diseases.
We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before.
Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world. If the answer is yes, then Editas Medicine is the place for you.
This new role on the Chemistry, Manufacturing, and Controls (CMC) team provides a unique opportunity to contribute to Editas’ efforts to develop safe and effective cellular therapies using CRISPR-based gene editing technologies. We are seeking a talented and highly-motivated individual to perform experiments that generate data to guide development of processing methods and standard operating procedures (SOPs) for the preparation of cellular therapies for translational clinical studies. This individual will also assist in the development and execution of isolation and cryopreservation procedures for various cell types (PBMCs, T cells, CD34+, etc.). Candidate must be experienced with aseptic technique and be versatile to assist in the development and execution of processes for normal donor cellular products derived from different lineages of cells. Candidate must be experienced with aseptic technique and be versatile to assist in the development of processes for autologous or normal donor cellular products derived from different lineages of cells (T cells, HSCs, etc.).
•Perform experimentation to develop cellular processes to support gene-edited cell therapy programs at Editas
•Isolate various cell types and cryopreserve cells to generate cells which support gene-edited cell therapy programs at Editas
•Assist in developing or improving isolation, cryopreservation, and post-thaw assessment methods for various cell types
•Assist in performing post-thaw analysis of cells to confirm suitability for use in research and development
•Assist in generating and maintaining cell inventories
•Assist in compiling and verifying data, data analysis, and drafting technical reports to support developed cellular processes for clinical manufacturing
•Work with Analytical Development to assist in the generation of samples and data to develop understanding of most relevant critical quality attributes of cellular products to guide safe and effective clinical testing and process control strategies
•Collaborate with internal teams to ensure cells isolated and cryopreserved support ex vivo program research and development needs
•Assist with the technical transfer of cellular manufacturing methods to Manufacturing or external CMOs
•Advanced life sciences degree and 1+ years of aseptic technique and cell culture, preferably including isolating, culturing, and freezing cells using automated equipment and closed processes
•Knowledge of blood and cellular analytical methods including complete blood counts with differentials, cell counting, and multi-color flow cytometry
•Strong organizational skills with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals in a fast-paced environment
•Strong verbal and written communication skills
•Attention to detail and the ability to work individually, within a multi-disciplinary team in a matrix environment, as well as with external partners
We are an equal opportunity employer offering a competitive salary and benefits package. All applicants should be legally entitled to work for any employer in the US.
Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.