Research Associate I/II, Immunogenetics – 1103 – Cambridge, MA

Job Description

What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases.

We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before.

Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.

The Immunogenetics team is looking to add highly talented and motivated candidates to assist in the development of novel immuno-oncology therapies for cancer. The team develops innovative cell-based anti-tumor strategies for cancer using gene editing and genetic engineering. The successful candidate will contribute as part of a dynamic, multidisciplinary discovery team dedicated to the development of novel first-in-class therapeutics. This position will serve a critical function in providing high-level laboratory support to project leads with a focus on cellular and molecular immunology. We are seeking a highly motivated and innovative research associate with cancer/ cell biology/ immunology background to support the development of gene editing-based therapies.

Key Responsibilities:
•Develop and optimize protocols for genetic engineering, including: vector design, cloning, viral delivery and tissue culture
•Characterize genetically modified cells using flow cytometry, imaging, Western blotting and RT-PCR
•Develop and perform immune cell activation, cytotoxicity, and other cellular and ELISA-based assays to evaluate gene editing approaches that improve the efficacy of effector cell therapeutics in vitro and in vivo
•Share responsibility in maintaining lab equipment and reagent inventory
•Analyze and present experimental data to laboratory staff and larger program meetings
•Maintain an electronic lab notebook and contribute to support documentation

Minimum Qualifications:
•B.S., M.S. in immunology, cell or molecular biology with 3-6+ years post-degree research experience
•Must have experience with mammalian cell culture including primary hematopoietic cells
•Strong preference for individuals with demonstrated knowledge of molecular cloning techniques and gene editing
•Experience in multi-color flow cytometry is desired
•Result-driven with excellent attention to details and ability to independently execute protocols
•Experience troubleshooting assays, including consulting the available literature for potential precedent
•Excellent written and oral communication skills
•Ability to work in a team-oriented, multidisciplinary environment

We are an equal opportunity employer offering a competitive salary and benefits package. All applicants should be legally entitled to work for any employer in the US.

Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.