Careers at Editas

Scientist I/II, Analytical Chemistry Group – Boulder, CO

Job Description

Location — Boulder, CO

What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We’re focused on translation the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases.

We’re looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before.

Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.

The Editas Chemistry Group in Boulder, Colorado focuses on three key areas. The first is fundamental research aimed at driving the design of the next generation of therapies. The second is process development on declared lead gRNAs to enable a streamlined path to manufacturing. The third is GMP manufacture of high-quality guide RNAs to support internal clinical programs and those of our collaborators.

This new role on the Analytical Chemistry team in Boulder provides a unique opportunity to contribute to Editas’ efforts through the analytical method development, assay development, and biophysical characterization of RNA and RNA/protein complexes.

Key Responsibilities:
• Work closely with the Medicinal Chemistry group at the Boulder Colorado site to develop characterization methods and solve key technical problems related to gRNAs
• Coordinate with Research Groups at Editas Headquarters in Cambridge to develop analytical characterization methods and solve key technical problems related to nucleic acid-protein complexes
• Author and review technical protocols and reports and maintain an ELN

Minimum Requirements:
• PhD in life sciences/Master’s degree in life sciences +3 years of experience in biotechnology
• experience with characterization of nucleic acids and development of characterization methods
• Strong organizational skills with the ability to multi-task, problem-solve, prioritize assignments, and adjust priorities to meet goals in a fast-paced environment
• Strong verbal, written and communication skills, including scientific presentations

Preferred Requirements:
• Experience with any of the following instrumentation and analytical techniques: HPLC/UPLC, PAGE, CGE, absorbance and fluorescence, mass spectrometry, and qPCR/NGS
• Knowledge of small molecule structure characterization (NMR, MS)
• Knowledge of CRISPR/Cas9 gene editing technologies
• Experience with analytical method qualification/validation